Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and. Amaç: İdiopatik trombositopenik purpura (ITP); trombositopenî, trombosit ömründe kısalma, plazmada anti-trombosit antikorların varlığı ve kemik iliğinde. Immune thrombocytopenic purpura (ITP) is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal.

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Secondary causes could be leukemia, medications e. Infobox medical condition new All articles lacking reliable references Articles lacking reliable references from July Recommendations of the American Society of Hematology. Hypo- coagulability Thrombocytopenia Thrombocytopenic purpura: For patient with active H. Durable remission following splenectomy is achieved in 75 percent of ITP cases.

Sudden and severe loss of blood from the digestive tract tromboeit occur. Fetal blood analysis to determine the platelet count is not generally performed as ITP-induced thrombocytopenia in the fetus is generally less severe than NAIT.

Immune thrombocytopenic purpura (ITP): MedlinePlus Medical Encyclopedia

There is no specific treatment for ITP. Medicine called danazol Danocrine taken by mouth Infusions of high-dose gamma globulin an immune factor Drugs that suppress the immune system Anti-RhD therapy for people with certain blood types Drugs that stimulate the bone marrow to make more platelets People with ITP should not take aspirin, ibuprofen, or warfarin, because these drugs interfere with platelet function or blood clotting, and bleeding may occur.

Immune thrombocytopenia, neonatal alloimmune thrombocytopenia, and posttransfusion purpura. ABC of clinical haematology. Splenectomy removal of the spleen may be considered in patients who are either unresponsive to steroid treatment, have frequent relapses, or cannot be tapered off steroids after a few months. Urea breath testing and stool antigen testing perform better than serology -based tests; moreover, serology may be false-positive after treatment with IVIG.


Immune thrombocytopenic purpura – From agony to agonist. Please review our privacy policy. First, it has to be determined that there are no blood abnormalities other than a low platelet count, and no physical signs other than bleeding.

Extraoral examination revealed petechial spots over the neck on right side [ Figure 1 ], petechial spots over the forearms, and petechial spots over the right arm [ Figure 2 ]. Views Read Edit View history. The acute form often follows an infection and has a spontaneous resolution within two months. With rare exceptions, there is usually no need to treat based on platelet counts. In adults, particularly those living in areas with a high prevalence of Helicobacter pylori which normally inhabits the stomach wall and has been associated with peptic ulcersidentification and treatment of this infection has been shown to improve platelet counts in a third of patients.

Immune thrombocytopenic purpura (ITP)

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Foreign Hemolytic disease of the newborn. Other biochemical examinations, liver function tests, and ultrasonography of abdomen were normal.

Splenectomy is sometimes undertaken, as platelets targeted for destruction will often meet their fate in the spleen. In a study conducted in Great Britainit was noted that ITP causes an approximately 60 percent higher rate of mortality compared to gender- and age-matched subjects without ITP.


Spontaneous remissions are unusual in adults. A report of 66 cases. The patient was followed-up for 2 years and there was no re-occurence reported.

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Discussion There is marked variability in the clinical presentation of ITP. As most causes appear to be related to antibodies against platelets, it is also known as immune thrombocytopenic purpura.

Immune thrombocytopenic purpura ITP. Current guidelines recommend treatment only in cases of significant bleeding.

Idiopathic thrombocytopenic purpura

Patients are also advised to avoid using aspirin or ibuprofen as pain relievers because these drugs lengthen the clotting time of blood. People with ITP should not take aspirin, ibuprofen, or warfarin, because these drugs interfere with platelet function or blood clotting, and bleeding may iidopatik. Systemic lupus erythematosus Subacute bacterial endocarditis Rheumatoid arthritis.

The clinical presentation may be acute with severe bleeding, or insidious with slow development with mild or no symptoms. It causes a characteristic purpuric rash and an increased tendency to bleed. ITP occurs when certain immune system cells produce antibodies against platelets. Two distinct clinical syndromes manifest as an acute condition in children and a chronic condition in adults.

Immune thrombocytopenia [1] ITP is a type of thrombocytopenic purpura defined as isolated low platelet count thrombocytopenia with normal bone idiolatik and the absence of other causes of thrombocytopenia.

Sometimes the body may compensate by making abnormally large platelets.

Last modified: January 2, 2020